Handshake AIDomain experts
Chemistry Expert
up to $125/hr
About this role, in Handshake AI's words
Handshake is looking for experienced chemists to support AI research through flexible, part-time contract work. This is not a traditional job — you'll draw on your hands-on experience in computational, physical, or theoretical chemistry to evaluate AI-generated content and provide feedback that helps AI reason like a practicing chemist.
What you'll do
- Use your domain expertise to create expert-level computational chemistry problems and scenarios grounded in real simulation, modeling, and reaction workflows
- Review and evaluate AI-generated responses for technical accuracy, reproducibility, and alignment with how the work is actually done
- Provide structured written feedback to help improve AI model performance
- Complete tasks at your own pace with no set schedule or minimum hour requirement
Candidate background
Qualifications
- Degree — Master or PhD in Chemistry or any related field. An MS paired with pharma or materials industry experience also qualifies
Additional qualifications (not required, but strengthen your application)Preferred
- Proficiency across multiple quantum chemistry, MD, and cheminformatics platforms
- Experience running production simulation or DFT pipelines in a pharma, materials, or energy research setting
Required for all applicants
- Must have US work authorization
- Strong written communication and attention to detail
- Ability to explain complex chemistry concepts clearly
- Ability to work independently in a remote, asynchronous environment
Quoted from selected sections of Handshake AI's posting. The full posting may state other conditions. Read the full posting
A closer look
More context, when you need it.
Full job descriptionThe original posting, in Handshake AI's words
Posted by Handshake AI, reproduced here so you can judge the role before clicking. Original posting ↗
Opportunity Overview
Handshake is looking for experienced chemists to support AI research through flexible, part-time contract work. This is not a traditional job — you'll draw on your hands-on experience in computational, physical, or theoretical chemistry to evaluate AI-generated content and provide feedback that helps AI reason like a practicing chemist.
This is an ongoing, project-based opportunity you can take on alongside your current role.
What You'll Do
• Use your domain expertise to create expert-level computational chemistry problems and scenarios grounded in real simulation, modeling, and reaction workflows
• Review and evaluate AI-generated responses for technical accuracy, reproducibility, and alignment with how the work is actually done
• Provide structured written feedback to help improve AI model performance
• Complete tasks at your own pace with no set schedule or minimum hour requirement
Qualifications
• Degree — Master or PhD in Chemistry or any related field. An MS paired with pharma or materials industry experience also qualifies
Additional qualifications (not required, but strengthen your application)
• Proficiency across multiple quantum chemistry, MD, and cheminformatics platforms
• Experience running production simulation or DFT pipelines in a pharma, materials, or energy research setting
Required for all applicants
• Must have US work authorization
• Strong written communication and attention to detail
• Ability to explain complex chemistry concepts clearly
• Ability to work independently in a remote, asynchronous environment
Working with Handshake AIPay, getting started and work, from Handshake AI's own pages
What the platform publishes in general. These are not extra terms confirmed for this particular role.
- Getting paid
- Paid weekly through Stripe. Handshake says it usually sends payouts by Wednesday afternoon for the previous Monday to Sunday week, and a payment can often take 48 hours to process and appear. Some projects set their own schedule. Non-US tax residents face 30% US withholding unless they certify the work was done outside the US. ai-support.joinhandshake.com/articles/32263614087575, ai-support.joinhandshake.com/articles/33238954868759, ai-support.joinhandshake.com/articles/39964143294615
- Before your first paid task
- Its pages give different answers on who can join. Its AI page says you must be based in the US, its help center says people outside the US can join by invitation only, and some of its postings ask for Indian work authorization or a base in Canada. Identity verification, tax details and a payout method come before paid work, and a failed assessment usually cannot be retaken. joinhandshake.com/ai, ai-support.joinhandshake.com/articles/37145099086743, joinhandshake.com/ai/opportunities/physics-expert-india, joinhandshake.com/ai/opportunities/ai-evaluation-speciali..., ai-support.joinhandshake.com/articles/32244754462615, ai-support.joinhandshake.com/articles/36935929970711, ai-support.joinhandshake.com/articles/41129932721431
- How much work
- Applying does not guarantee a project, and there is no fixed timeline for an invitation. Projects can start, pause or end at short notice. ai-support.joinhandshake.com/articles/32244169079703, ai-support.joinhandshake.com/articles/33238954868759, ai-support.joinhandshake.com/articles/38150760132119
- Contract
- Contractor, under an agreement with Handshake AI Solutions, LLC that says you are not an employee. joinhandshake.com/legal/contractor-agreement
Read on the pages linked above on 24 Sep 2026. Platforms change these terms, so check the linked page before you rely on one.
How does the pay compare?Across Domain experts roles, not this role alone
From our own daily reads of every open listing on the platforms we follow, not from Handshake AI's posting. How we count.
Pay across the field: Domain experts
Across 751 roles in this field with a stated hourly rate in US dollars, on 21 platforms, the middle half pays $63 to $125 an hour at the top of the range, and the median is $100. This role's top rate, $125, is in the top quarter. Of the 268 distinct rates we count, 198 are lower and 65 are higher.
| Platform | Roles | Top of range, per hour |
|---|---|---|
| micro1 | 155 | $12 to $400 · median $110 |
| Alignerr | 148 | $24 to $200 · median $80 |
| AfterQuery | 93 | $45 to $175 · median $100 |
| Mercor | 90 | $55 to $450 · median $120 |
| Handshake AI (this platform) | 80 | $30 to $300 · median $80 |
Sources and listing historyWhere this information comes from
This listing's history
- First seen here on 8 Sep 2026, and still on Handshake AI's list when we last read it on 25 Oct 2026.
- Listed pay changed on 29 Sep 2026: up to $75/hr before, up to $125/hr after.
A change can also be a correction to how we read Handshake AI's feed. The figure at the top of this page is always the latest read.
- Posted by Handshake AI
- First seen by AIPayList
- Last seen live
- Listing ID
- 11389498
Pay as the source states it: “Up to $125/hr”.
Platforms sometimes change a rate after posting. Every listing here is re-read at least once a day and corrected when its source moves, so a difference you see on the platform is usually a change made since the last read. How freshness works.
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